VALIDATED KINETIC SPECTROPHOTOMETRIC DETERMINATION OF PITAVASTATIN CALCIUM USING ACIDIC PERMANGANATE OXIDATION
نویسندگان
چکیده
منابع مشابه
Kinetic spectrophotometric method for the determination of silymarin in pharmaceutical formulations using potassium permanganate as oxidant.
A new simple and sensitive kinetic spectrophotometric method for the determination of silymarin in pure form and in pharmaceutical formulations is described. The method is based on the oxidation of the drug with potassium permanganate at pH 7.0 +/- 0.2. The reaction is followed spectrophotometrically by measuring the decrease in the absorbance at 530 nm. The calibration graph is linear in the r...
متن کاملKinetic Spectrophotometric Method for Determination of S032- Using Methylen blue
The present work reports a kinetic spectrophotometric method for the determination of traceamounts of sulphite that is based on inhibitory effect of sulphite on the oxidation of Methyleneblue (MB) in acidic media. The reaction is followed spectrophotometrically by monitoring thedecrease in absorbance of MB at 664 nm with a fixed time of 0.5-4.5 minutes. It was found thatsulphite exert a strong ...
متن کاملKinetic spectrophotometric determination of trace amounts of nitrite ion using potassium bromate-murexide mixture in acidic media
A new, simple, rapid, and cheap method for determination of trace amounts of nitrite ion is reported.Determination is based on reduction of bromate ion by nitrite ion, in the presence of murexide inacidic media. During reaction of bromate ion with nitrite ion, the reaction mixture is decolorized.The absorbance changes is then monitored spectrophotometricaly at 520 nm, at 25 °C. Dynamicrange of ...
متن کاملOxidation of levofloxacin by acidic permanganate: a kinetic and mechanistic study
The kinetic and mechanistic investigation of oxidation of levofloxacin (LF) has been studied by permanganate ion in aqueous sulphuric acid medium at 25°C. The reaction followed first-order kinetics with respect to [LF], and [H+] in their lower concentrations range, tending to zero-order at their higher concentrations. The effect of added products and dielectric constant of the medium was studie...
متن کاملKinetic-spectrophotometric determination of trace amounts of silver using the oxidation of thionine with peroxodisulfate.
A simple, rapid and sensitive method has been developed for determination of traces of silver(I) (0.2 - 13 ng mL(-1)) based on its catalytic effect on the oxidation of thionine by peroxodisulfate in the presence of 1 - 10 phenanthroline as an activator. The reaction is monitored spectrophotometrically by measuring the decrease in absorbance of thionine at 600 nm by the fixed time method. The de...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmacy and Pharmaceutical Sciences
سال: 2020
ISSN: 0975-1491,2656-0097
DOI: 10.22159/ijpps.2020v12i3.35888